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Triptorelin

CBNumber: CB2366465
Chemical Name: TRIPTORELIN
Molecular Formula: C64H82N18O13
Formula Weight: 1311.45
CAS No.: 57773-63-4
Certification: HPLC/MS
Appearance: white power
Min order:1kit
Shelf Date:24 months
Specification: 2mg/vial 10vials/kit
alpha D23 -58.8° (c = 0.33 in acetic acid)
storage temp. −20°C
form powder
InChIKey HPPONSCISKROOD-OYLNGHKZSA-N
CAS DataBase Reference 57773-63-4(CAS DataBase Reference)

What is triptorelin?

1.Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gona-dotropin-releasing hor-mone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gona-dotropins luteinizing hor-mone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. It is also used as therapy in cases of gender dysphoria.

2.During the treatment of prostate cancer it does cause a surge of testosterone (an initial uplevel of testosterone levels), known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy. In contrast, gona-dotropin-releasing hor-mone antagonists do not cause a surge, but a sudden reduction of tes-T levels

3.Triptorelin is a man-made form of a hormone that regulates many processes in the body. Triptorelin overstimulates the body’s own production of certain hormones, which causes that production to shut down temporarily.

Triptorelin is used to treat the symptoms of prostate cancer. Triptorelin treats only the symptoms of prostate cancer and does not treat the cancer itself. Use any other medications your doctor has prescribed to best treat your condition.

Triptorelin may also be used for purposes not listed in this medication guide.

Although triptorelin is not for use by women, this medication can cause birth defects and should not be used by a woman who is pregnant or who may become pregnant.

tri HPLC_01

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