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Pharmaceutical Name: Dianabol

Chemical Name: Methandienone

Chem.Abstr.Name: 17beta-hydroxy-17alpha-methylandrosta-1,4-dien-3-one

Molecular Structure: C20H28O2

Molecular Weight: 300.4

Androgen Index 40-60

Anabolic index 90-210

Maternal hormone methyltestosterone (oral)

Chemical name 17a-methyl-17b-hydroxy-1,4-androstadien-3-one,1-dehydro-17a-methyltestosterone

Moderate estrogenic activity

Progesterone activity was not significant

High bioavailability

Metabolic pathway liver

Half-life 3-6 hours

Excretion route Urine

Introduction of Dianabol:

Dianabol is the most well-known trade name for the drug metosterone, a derivative of testosterone that has been modified to reduce the hormone's androgenic (masculine) properties while maintaining its anabolic (tissue-building) properties. With lower levels of relative androgen compared to testosterone, the drug is designed and marketed primarily as an oral drug, although it can also be found in many injectable veterinary drugs. Dianabol today is the most commonly used oral anabolic/androgenic steroid in history for building physique and improving performance.

Dianabol Product History:

In the 1940s and 1950s, the Soviet Union began to dominate the Olympics, and the use of testosterone by many athletes left the rest of the world far behind. During this time, Dr. John Ziegler of the U.S. Olympic team will learn about steroid use in the Soviet Union and quickly help ensure his athletes are matched. In 1958, with the help of Dr. Ziegler, Ciba Pharmaceuticals would release the first batch of Methandrostenolone (Methandrostenolone) under the trade name Dianabol. Dianabol maintains the anabolic properties of testosterone while reducing androgenic hormones in a fast and effective way. The advent of Dianabol has led to great success for American athletes, giving many American athletes a distinct advantage over their Soviet competitors.

Dr. Ziegler's athletes quickly made huge strides in their competitive careers with the help of drugs. In the early 1960s, Dianabol sparked a wave of steroid abuse in competitive sports. Dr. Ziegler's recommended dosage suggests a daily dose of 5mg or 15mg, but is largely ignored by athletes, many of whom use super-dose Dianabol. Dr. Ziegler quickly became disgusted with substance abuse and eventually became a voice against sports doping. By 1967, some 10 years after Dianabol was first introduced to athletes, he explicitly condemned the use of anabolic steroids in sports.

Dianabol was already under scrutiny by the U.S. Food and Drug Administration as early as 1965. That year, the FDA asked Ciba to clarify the medical use of Dianabol, which Ciba said included helping debilitated patients and those with weakened bones. In 1970, the FDA accepted Dianabol as "possibly effective" in the treatment of postmenopausal osteoporosis and pituitary deficient dwarfism, and allowed Ciba to continue to market and study the drug. However, Ciba eventually lost its patent protection, and companies like Parr, Barr, Bolar and Rugby were quick to penetrate the market with their own generic versions of the drug.

By the early 1980s, the FDA had withdrawn its "possibly effective" stance on pituitary deficiency dwarfism, and in 1983, Ciba officially pulled Dianabol from the U.S. market. The U.S. Food and Drug Administration withdrew all generic forms of Dianabol from the U.S. market in 1985, at a time when most Western countries were also eliminating the drug, arguing that its primary use was for sports doping. Illustration: (middle)

Dianabol Structural Features:

Dianabol is a modified form of testosterone. It differs in: the addition of a methyl group at carbon 17-alpha to protect the hormone during oral administration; the introduction of a double bond between carbons 1 and 2, which reduces its relative androgenicity. The resulting steroid also had a much weaker relative binding affinity to the androgen receptor than testosterone, but simultaneously displayed a longer half-life and lower serum binding protein affinity. These characteristics (among other things) make Dianabol a very potent anabolic steroid despite a weaker affinity for receptor binding. Recent studies have also confirmed that its primary mode of action involves interaction with cellular androgen receptors.

The effects of Dianabol can be summarized as rapid onset and explosive growth. In fact, individuals who use Dianabol for the first time can quickly gain up to 20 pounds within a few weeks of use, making Dianabol an off-season steroid that would be its most common use. . Dianabol also produces a significant increase in strength during this phase of use.

Dianabol Side Effects: Estrogen

Dianabol is a relatively strong estrogenic anabolic steroid because it carries moderate aromatase activity. Although its aromatase activity is only moderate, this conversion actually results in the conversion of Dianabol to methylestradiol rather than estradiol, which is much stronger than estradiol. Side effects like gynecomastia and water retention can be noticeable with this steroid; in fact, they can appear to appear overnight. Heavy water storage can also promote high blood pressure, for which Dianabol is notorious. Such effects are manageable, and when it comes to high blood pressure, you need to put in some effort to make sure it doesn't become a problem.

Dianabol Side Effects: Androgens

Dianabol is not an extreme androgenic steroid and its androgenicity has been structurally reduced, but androgenic side effects are still possible. Possible side effects of using Dianabol include acne, accelerated hair loss and increased body hair growth in men who are prone to male pattern baldness and those with hereditary alopecia, and irritability. Most people do not experience the above side effects, although a small number of people do. This effect is caused by the metabolism of Dianabol by 5-alpha reductase.

Dianabol Side Effects: Cardiovascular System

Dianabol has a significant negative effect on cholesterol. This includes suppression of HDL cholesterol and increases in LDL cholesterol, and the overall change may be significant. Total cholesterol levels may remain within a healthy range, but if HDL is severely suppressed, resulting in an imbalance in cholesterol levels, total cholesterol levels are often shown to be normal and misleading. It is very important to control cholesterol while using Dianabol. As with many anabolic steroids, repeated use of this steroid may cause the accumulation of lipid plaques in the arteries over time. It is also important to keep in mind that when using Dianabol, using an aromatase inhibitor AI can cause additional stress on cholesterol, as the reduction in total estrogen can have a negative effect.

As mentioned above, Dianabol can also have a negative effect on blood pressure, in most cases because of the increased blood pressure caused by the water storage caused by Dianabol. If you already have high blood pressure or high blood lipids, you should no longer use this steroid. If you are healthy enough, you should make sure your lifestyle is conducive to their use. This should include a healthy diet rich in omega fatty acids, adequate aerobic exercise, and a regular schedule. Control of estrogen levels is also very important because estrogen plays an important role in cholesterol regulation

Dianabol side effects: Inhibition of own testosterone secretion

All anabolic steroids suppress natural testosterone production. While the overall rate of inhibition varied from one steroid to the next, it was very noticeable with Dianabol. For this reason, some form of exogenous testosterone is added to Dianabol use in most cycles. Excluding exogenous testosterone can lead to low levels of native testosterone. This condition comes with complications and is very unhealthy. Even if symptoms don't appear, low testosterone levels are still unhealthy and very bad for muscle growth, and if you include the use of exogenous testosterone, the problem goes away.

With Dianabol, including all anabolic steroids, natural testosterone production will begin to recover again after discontinuation. While natural recovery will begin on its own, it will be slow. For this reason, most people schedule a pct after the cycle to help the body recover.

Dianabol side effects: Liver toxicity

Dianabol is a C17-alpha alkylated anabolic steroid and is therefore hepatotoxic. Hepatotoxicity varies widely with each C17-aa steroid, and while Dianabol is far from the most toxic, we can’t call it mild either. However, its total toxicity should not lead to liver damage if responsible use is followed and the liver itself does not have any disease problems. Levels of liver enzymes will increase during use, but it is important to remember that increased levels of liver enzymes do not equal damage, but are a proxy for increased liver stress. Under normal circumstances, the use cycle of Dianabol is generally 6 weeks.

There are a few things to consider for your health. When using a C17-aa steroid like Dianabol, it is very important to avoid drinking too much alcohol, which puts a lot of pressure on the liver. Keep in mind that alcohol is probably the most resistant substance in our body and has a huge negative impact on our body, and the purpose of our use of Dianabol is to enhance our physical performance and capabilities. In addition to alcohol, over-the-counter (OTC) medications should be avoided whenever possible. Many OTC medications have a strong stress on the liver, in some cases, much more so than many anabolic steroids, and liver supplements should be used for a period of time after use to keep the liver healthy.

Use of Dianabol:

Dianabol dosages vary widely based on experience and individual needs. Although there is a lot of discussion about the dosing of Dianabol, basically only 15mg of Dianabol per day can produce significant results. However, most people will be more satisfied with a dose of 20-25mg per day. Remember, every time we increase the dose, we also increase the likelihood of side effects and make them harder to control. If enjoying a positive experience in the 20-25mg dose range, try 30-35mg per day if needed. 50mg per day would be the next step, which is a larger dose of Dianabol typically used by seasoned anabolic steroid users. However, many people do not need such doses. Higher doses are not uncommon in some hardcore circles, you can easily find someone using 100mg a day, but this dose is not recommended. Dosages of this nature can have side effects that can be harmful to your health. Even if you can take that dose and have no side effects, but it's often just no visual side effects, the inside can be a very different story.

Dianabol has a half-life of 3-5 hours, and many recommend dividing the daily dose into 2-3 doses per day to maintain blood levels of the drug. However, even when the same dose is taken three times a day, the blood level of the drug will still fluctuate. Furthermore, the maximum peak blood level will be much lower than the highest blood level possible if the total doses were administered simultaneously. By taking the total day dose right away, this will give you higher peak blood levels that you can maximize during training time and critical time windows after training. No matter which method you choose, you will find that Dianabol can produce great results.

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